What is 2-bromo-2-nitropropane-1,3-diol(bronopol)，Cas No 52-51-7?

Bronopol CAS 52-51-7 , chemical name 2-bromo-2-nitro-1,3-propanediol. White crystalline powder, Melting Point: 122~130℃. Easily soluble in water, ethanol, propylene glycol, ethyl acetate, etc., slightly soluble in oil, difficult to dissolve in chloroform, acetone, etc.

Bronopol is an antimicrobial, with low mammalian toxicity (at in-use levels) and high activity against bacteria (especially the troublesome Gram-negative species).

Bronopol appears as white crystals. Ignite easily and burn readily. May detonate under strong shock. Decomposes when heated, evolving toxic gases. Toxic by skin absorption, inhalation or ingestion.

Bronopol is an organic compound with wide-spectrum antimicrobial properties. First synthesized in 1897, bronopol was primarily used as a preservative for pharmaceuticals and was registered in the United States in 1984 for use in industrial bactericides, slimicides and preservatives. Bronopol is used as a microbicide or microbiostat in various commercial and industrial applications, including oil field systems, air washer systems, air conditioning or humidifying systems, cooling water systems, papermills, absorbent clays, metal working fluids, printing inks, paints, adhesives and consumer products. Compared to other aliphatic halogen-nitro compounds, bronopol is more stable to hydrolysis in aqueous media under normal conditions. The inhibitory activity against various bacteria, including Pseudomonas aeruginosa, was demonstrated in vitro. The agent is largely available commercially as an antibacterial for a variety of industrial purposes while it is predominantly available for purchase as a pet animal litter antibacterial at the domestic consumer level. Nevertheless, ongoing contemporary re-evaluations of bronopol use in large markets such as Canada now place various compositional and product restrictions on the use of the agent in cosmetic products and in other products where it may not primarily be used in the role of a non-medicinal preservative antimicrobial. Bronopol is a Standardized Chemical Allergen. The physiologic effect of bronopol is by means of Increased Histamine Release, and Cell-mediated Immunity.

What are the application areas of bronopol?

Bronopol is effective against a wide range of plant pathogenic bacteria and is mainly used as a seed treatment agent, etc. In addition, because of its broad-spectrum antibacterial property, it has been used as a disinfectant in medicine in the 60 s of the last century. With the increasing development of cosmetics, coupled with broad-spectrum antimicrobial, and water-soluble, into the late of the 20th century, 80 s, as a cosmetic preservative use and rapid development. In recent years, bropole has been widely used in feed, paint, fur anti-corrosion, air conditioning circulating water antibacterial, oil field water injection antibacterial and aircraft, ship Disinfection and other aspects, the demand increased rapidly. Mainly used in medical disinfectants, cosmetics preservatives, can also be used as pesticide treatment agents.

1. As a broad-spectrum antimicrobial agent of bronopol type, it has the following characteristics: spectrum antibacterial activity, in the range of pH 4~9 in emulsion products containing surfactants, and high concentration of protein substances in the formula, with effective antibacterial activity, especially for the antibacterial activity of Pseudomonas aeruginosa has special effects; Non-toxic, non-irritating, non-allergic, the dosage of the preservative in cosmetics is 0.01% ~ 005%, and the toxicity test results show that the preservative is safe and is one of the cosmetic preservatives approved by FDA in the United States. According to the U. S. FDA statistics, among all the preservatives used in cosmetics, brogpole's frequency of use ranked first. It is the sharp increase in commercial demand, which has promoted the research and industrial production of brospar.

2. Bactericide. It can effectively control a variety of plant-pathogenic bacteria. The treatment of cotton seeds can prevent cotton black arm disease and bacterial blight disease caused by cotton angular leaf spot fungus and has no damage to cotton. It can also be used for rice seedling disease. It is recommended to use the concentration of 800 ~ 1000mg/L. mainly used for cosmetics, leather anti-corrosion, in agriculture is mainly used for prevention and control of rice seedling disease biocide, mainly used in industrial circulating water, paper pulp, paint, plastics, cosmetics, wood, cooling water circulation system, and industrial use of sterilization, anti-mildew, anti-corrosion, algae, etc.

3. Widely used in water treatment, pharmaceuticals, pesticides, cosmetics, detergents and other industries as preservatives and sterilants cosmetics preservatives, added in shampoo, Balsam and cream and other cosmetics processing, bactericidal concentrations in cosmetics range from 0.01% to 0.02%. It can also be used for detergents, fabric treatment agents, etc.

4. A broad-spectrum and efficient industrial fungicide used to prevent the growth and reproduction of bacteria and algae in paper making, industrial circulating cooling water, lubricating oil for metal processing, Pulp, wood, paint and plywood, at the same time can do slime control agent, widely used in paper mill pulp and circulating cooling water system.

   
   

1. Bronopol is our regular export product, we have more than 120 tons of production capacity per month.

3. Bronopol belongs to Class 4.1 dangerous goods, and SINOBIO is very confident in Class 4.1 dangerous goods shipping.

Dalian Sinobio Chemistry Co.,ltd is committed to continuous improvement and innovation. We invest in research and development to stay at the forefront of the biocides/water treatment chemical industry, constantly exploring new technologies and solutions to meet the evolving needs of our customers.

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