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PHMB 27083-27-8
SINOBIO
Name: Poly(hexamethylenebiguanide)hydrochloride/PHMB
CAS: 27083-27-8/32289-58-0
Chemical formula: C10H23N5
Appearance: White Powder
MW: 213.32312
Purity: 98%
PHMB is widely used in medicine for sterilization and antisepsis.It is also widely used in cosmetics, personal care products, textiles, food industry, etc.With the development of science and technology, , it is used as a flocculant, as a bactericide in swimming pools and industrial water treatment, as a bactericide in oil recovery water injection, and can clean and remove harmful substances from glassware and other hard surfaces.
PHMB is best known for its broad-spectrum antimicrobial and antifungal activity. It is the standard of care for treatment of Acanthamoeba keratitis and an ingredient in multipurpose contact lens solutions, such as Renu (Bauch & Lomb, Rochester, NY). PHMB is a cationic disinfectant that is effective against Gram-negative and Gram-positive bacteria through its electrostatic interaction with negative sites on the lipopolysaccharide component of bacterial cell membranes.
| Item | Specification |
| Appearance | White pwder |
| pH(1% water solution)25ºC | 5.34 |
| Ratio of absorbance (237nm/222nm) | 1.58 |
| Light absorption value (1%,237nm) | 40 |
Polyhexamethylene biguanide hydrochloride (PHMB) is a broad-spectrum antimicrobial and disinfectant used in a wide range of applications. The following are some of the major application areas of PHMB:
1. Pharmaceuticals: PHMB is widely used in pharmaceutical products such as contact lenses, eye drops and surgical disinfection. It is also used in the treatment of echinococcal amebic keratitis and in the prevention of other eye diseases. Due to its good biocompatibility with host cells, PHMB is also used in wound cleaning, sterilisation of medical equipment and medical dressings.
2. Hygiene field: PHMB can effectively prevent the spread of infectious diseases, so it is widely used in hand hygiene products, disinfection of public places, water treatment and air cleaning.
3. Cosmetics and personal care products: PHMB is often used in skin care products and toiletries, such as facial cleanser, shampoo, shower gel, etc., because of its broad-spectrum bactericidal effect and low toxicity.
4. Textile field: PHMB is also used in medical textiles, sportswear and outdoor products to ensure the hygiene and safety of the products.
In addition, PHMB is also used in the food industry and animal husbandry and other fields for sterilisation and disinfection due to its broad-spectrum bactericidal efficacy and good antimicrobial performance.
Overall, PHMB has important applications in many fields such as medical, hygiene, cosmetics and textiles due to its excellent antimicrobial properties and wide application prospects. Also, due to its low toxicity and high safety, PHMB is considered an ideal choice of disinfectant.
* Polyhexanide (polyhexamethylene biguanide,PHMB) is a polymer used as a disinfectant and antiseptic.
In dermatological use, it is spelled polihexanide (INN) and sold under names such as Lavasept, Serasept, Prontosan and Omnicide. PHMB has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).
* Broad spectrum antimicrobial polymer; binds and disrupts cytoplasmic membranes.
Name: Poly(hexamethylenebiguanide)hydrochloride/PHMB
CAS: 27083-27-8/32289-58-0
Chemical formula: C10H23N5
Appearance: White Powder
MW: 213.32312
Purity: 98%
PHMB is widely used in medicine for sterilization and antisepsis.It is also widely used in cosmetics, personal care products, textiles, food industry, etc.With the development of science and technology, , it is used as a flocculant, as a bactericide in swimming pools and industrial water treatment, as a bactericide in oil recovery water injection, and can clean and remove harmful substances from glassware and other hard surfaces.
PHMB is best known for its broad-spectrum antimicrobial and antifungal activity. It is the standard of care for treatment of Acanthamoeba keratitis and an ingredient in multipurpose contact lens solutions, such as Renu (Bauch & Lomb, Rochester, NY). PHMB is a cationic disinfectant that is effective against Gram-negative and Gram-positive bacteria through its electrostatic interaction with negative sites on the lipopolysaccharide component of bacterial cell membranes.
| Item | Specification |
| Appearance | White pwder |
| pH(1% water solution)25ºC | 5.34 |
| Ratio of absorbance (237nm/222nm) | 1.58 |
| Light absorption value (1%,237nm) | 40 |
Polyhexamethylene biguanide hydrochloride (PHMB) is a broad-spectrum antimicrobial and disinfectant used in a wide range of applications. The following are some of the major application areas of PHMB:
1. Pharmaceuticals: PHMB is widely used in pharmaceutical products such as contact lenses, eye drops and surgical disinfection. It is also used in the treatment of echinococcal amebic keratitis and in the prevention of other eye diseases. Due to its good biocompatibility with host cells, PHMB is also used in wound cleaning, sterilisation of medical equipment and medical dressings.
2. Hygiene field: PHMB can effectively prevent the spread of infectious diseases, so it is widely used in hand hygiene products, disinfection of public places, water treatment and air cleaning.
3. Cosmetics and personal care products: PHMB is often used in skin care products and toiletries, such as facial cleanser, shampoo, shower gel, etc., because of its broad-spectrum bactericidal effect and low toxicity.
4. Textile field: PHMB is also used in medical textiles, sportswear and outdoor products to ensure the hygiene and safety of the products.
In addition, PHMB is also used in the food industry and animal husbandry and other fields for sterilisation and disinfection due to its broad-spectrum bactericidal efficacy and good antimicrobial performance.
Overall, PHMB has important applications in many fields such as medical, hygiene, cosmetics and textiles due to its excellent antimicrobial properties and wide application prospects. Also, due to its low toxicity and high safety, PHMB is considered an ideal choice of disinfectant.
* Polyhexanide (polyhexamethylene biguanide,PHMB) is a polymer used as a disinfectant and antiseptic.
In dermatological use, it is spelled polihexanide (INN) and sold under names such as Lavasept, Serasept, Prontosan and Omnicide. PHMB has been shown to be effective against Pseudomonas aeruginosa, Staphylococcus aureus (also the methicillin-resistant type, MRSA), Escherichia coli, Candida albicans (yeast), Aspergillus brasiliensis (mold), vancomycin-resistant enterococci, and Klebsiella pneumoniae (carbapenem-resistant enterobacteriaceae).
* Broad spectrum antimicrobial polymer; binds and disrupts cytoplasmic membranes.
